CANNABIDIOL
It is a cannabinoid, a type of compound found in the cannabis plant which is used to treat seizures, severe pain, and muscle spasms.
What is Cannabidiol used for?
- Epilepsy associated with Lennox-Gastaut syndrome or Dravet syndrome.
- Epilepsy associated with Tuberous sclerosis complex.
How is Cannabidiol available?
Oral Solution/ Syrup
Capsules (not available in India)
How does Cannabidiol act (mechanism of action)?
Cannabidiol (CBD) works by interacting with the endocannabinoid system and other receptors to regulate pain, inflammation, mood, and seizures.
How much time does Cannabidiol take to act?
Cannabidiol (CBD) typically takes 30 minutes to 2 hours to take effect.
Why is Cannabidiol important for you/your child’s treatment?
It is important that your child takes Cannabidiol regularly so that you/your child doesn’t suffer from Seizures or have fewer seizures episodes and other diseases.
Cannabidiol controls seizures but doesn’t cure epilepsy and works only while you keep taking it. So do not stop giving acetazolamide all of a sudden, as it may result in having more seizures.
What is the ideal time to take Cannabidiol?
CBD should ideally be taken twice a day, 10-12 hours apart (e.g., 7-8 am and 7-8 pm). Follow your doctor’s advice if a thrice-a-day regimen is recommended, and aim for consistent timing daily to establish a routine and reduce missed doses.
When should Cannabidiol be taken?
Cannabidiol (CBD) can be taken either before or after food. Taking it after food, especially fatty foods, can improve absorption. On an empty stomach, it may act faster but might be less absorbed.
How should I give the medicine?
Capsules: A whole tablet must be swallowed with a glass of water, juice or milk. You may give it by crushing and mixing it in water/ juice or small serving of yogurt / Curd. Liquid or syrup: Use an oral syringe or a medicine spoon to measure the adequate amount. You can easily get these from any pharmacy nearby. Do not use a kitchen teaspoon as it will not give the accurate amount of the drug.What if I miss a dose?
If you miss the dose, it can be taken as soon as you remember within the lapse of 6 hours. Do not take the missed dose if it is close to the next one; just take the next dose as normal. If you miss two or more doses, discuss with your doctor.
NEVER GIVE A DOUBLE DOSE OF CANNABIDIOL
If your child vomits out the content within 30 minutes of taking the medicine dosage then you can give the dose again; but if your child vomits after 30 minutes of taking the dose, then just leave it be and do not give it again.
Could this medication have any side effects on my child?
Every medication has both positive and potential negative effects. Fortunately, adverse effects are not common for everyone, but it’s essential to be aware of them. Understanding possible side effects allows us to act quickly and effectively if they occur, ensuring that we can address any concerns promptly while continuing to benefit from the intended effects of medications.
Even though it may be rare, few people sometimes may have serious side effects when taking a drug. Consult your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
SIDE EFFECTS:
Common Side Effects:
- Skin rashes.
- Losing weight.
- Feeling less hungry, upset stomach with diarrhoea or vomiting.
- Low red blood cell count (anaemia).
- Liver problems (shown by higher liver enzyme levels).
- Feeling tired, sleepy, or drained of energy.
- Fever.
- Urinary tract infections.
- Lower number of blood-clotting cells (platelets).
- Changes in behavior, like becoming irritable or aggressive.
Rare Side Effects (Less than 1%):
- Serious liver problems (very high enzyme levels).
- Red, itchy skin.
- Severe allergic reactions causing swelling (angioedema).
If your child starts developing skin Rash, Stop Medications right there and SEEK IMMEDIATE MEDICAL ADVICE from your DOCTOR
Sometimes your child may experience other side-effects that are not listed above. If you notice any abnormalities with your child’s body or behaviour, do not hesitate and immediately contact your doctor.
Can other common medicines be taken during the course of Cannabidiol?
Medications such as ibuprofen, paracetamol, and antibiotics, or any other over-the-counter medicines, can be used, when necessary, unless specifically prohibited by your doctor. Always consult with your doctor before administering any other medications to your child, including herbal or complementary remedies.
Certain medications used to treat epilepsy may impact the effectiveness of cannabidiol or lead to side effects. If your child experiences more seizures or any other adverse effects after using other medications, contact your doctor immediately.
What food to avoid while taking Cannabidiol?
When taking cannabidiol (CBD), there are a few foods and substances to be cautious of due to their potential interactions with CBD or their impact on its absorption and effects: To get the most out of CBD, it’s recommended to avoid grapefruit, be mindful of high-fat foods (which can increase absorption), and exercise caution when combining CBD with alcohol or caffeine. A balanced, healthy diet will also support your body’s overall function and may help optimize CBD’s effects.PREGNANCY AND LACTATION:
CBD should be avoided during pregnancy and lactation due to limited research and potential risks to Fetal and infant development. Always consult a healthcare provider before using CBD during these times.
Is there any risk if I conceive while taking Cannabidiol?
There may be potential risks if you conceive while taking CBD due to limited research on its effects during pregnancy. It’s recommended to consult a healthcare provider.
Can I stop taking Cannabidiol (Withdrawal)?
Withdrawal from Cannabidiol is not commonly associated with severe effects, but stopping it abruptly can lead to potential issues, particularly if it was being used for conditions like glaucoma, epilepsy, or altitude sickness.
Where should I keep this medicine?
- Keep the medicine in a cupboard, secured away from heat and direct sunlight. It is not a must to keep the medicine in the refrigerator though.
- Make sure the medicine is out of your child’s reach.
- Store the medication in the same box it was packed in.
For more information, please take a look at the manufacturer’s information leaflet.
MONITORING PARAMETERS
- Liver function test
- Signs and symptoms of CNS depression and behavioural changes, or suicidal ideations.